The capsule is easy to give to your dog and may be given as an occasional dose when you see fleas on your pet or daily if necessary. advantus™ contains 7.5 mg or 37.5 mg of imidacloprid. ● advantus™ may be used together with other products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos. Be sure to tell your veterinarian about any medications (including vitamins, supplements, or herbal therapies) that your pet is taking. Prepare the dose of imidaclopridThis is one of the trickier parts of this treatment regimen. Side effects are uncommon but may include vomiting, diarrhea, lack of appetite, tiredness, reddening of the skin, or itchiness. The adult dosage for most cats is 0.4 mL of the imidacloprid oil. Advantus Soft Chews are flavored, and may be fed easily by hand. Side effects are uncommon, but may include skin irritation at the application site. Increasing both the dose and the number of dosages of moxidectin improved efficacy, with 100% protection obtained using three dosages of moxidectin at either 40 µg/kg (JYD-34, ZoeMO) or 60 µg/kg (ZoeLA). Side effects of fipronil and when to report them. Oral dosage forms require careful pharmaceutical formulation. Three dosages of 24 µg/kg were also highly effective, providing ≥ … Your veterinarian may monitor your pet to be sure that the medication is working. Frontline Plus Flea and Tick Control for Cats and Kittens. Weight of cat [kg] Pipette size to be used Volume [ml] Imidacloprid [mg/kg bw] Use: advantus™ kills adult fleas and is indicated for the treatment of flea infestations on dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater. We comply with the HONcode standard for trustworthy health information -, advantus (imidacloprid) soft chew Indications, Warnings and cautions for advantus (imidacloprid) soft chew, Direction and dosage information for advantus (imidacloprid) soft chew. The following diagram illustrates the flea’s life cycle and where advantus™ works: Fleas reproduce rapidly. Give the missed dose as soon as you remember, and then wait the recommended amount of time between doses. This medication will take effect quickly, in about 1 to 2 hours, and improvement in clinical signs should follow. Bayer Healthcare LLC, Animal Health Division, Shawnee Mission, KS 66201 USA, Bayer (reg’d), the Bayer Cross (reg’d) and advantus™ are registered trademarks of Bayer. ● advantus™ has not been tested in pregnant or nursing dogs. Before using or dispensing any product, read and carefully observe the label directions. Flea control with 3.75 mg of imidacloprid/kg of body weight ranged from 94.4 to 96.9% for days 14 to 28 and decreased to 91.6% by 34 days after treatment. Find helpful customer reviews and review ratings for Advantus (imidacloprid) Oral Dog Flea Treatment, Soft Flea Chews for Dogs 23-110 lbs, 30 doses at Amazon.com. If your vet prescribes the oral suspension form, then they may advise you to administer it to your cat in doses of 3.4 milligrams per pound of body weight. ● advantus™ does not protect against ticks or mosquitoes. Directions: You should weigh your dog before giving this medication to make sure you are using the right size for your dog. Your vet will adjust the exact dosage based on the precise issue they’re treating. Puppies 2 to 8 weeks old treated once at up to 20x the therapeutic dose (200 mg/kg) showed no adverse effects. It is frequently used in combination with other medications to treat a variety of parasites. Imidacloprid is an insecticide and therefore can cause toxicity in your dog. Description. To report side effects, call Bayer Veterinary Services at 1-800-422-9874. Never give your dog two doses at once or give extra doses. This is especially the case if your dog is sick or already debilitated from an illness. Do not apply to irritated skin. 1. Certain combination products should be used in cats. Precautions and Side Effects. Adult female fleas feed by ingesting blood from your dog and lay eggs that drop off from your dog’s coat. Updated: 2020-12-31. (Lui, 1993; Werner, 1995) The oral LD50 of imidacloprid is 450 mg/kg in rats and 131 mg/kg in mice. Dogs that have abnormally low … Imidacloprid is given by mouth to treat flea infestations in dogs only. As specified in the following table, administer the entire contents of the Advantage Multi® for Catstube that correctly corresponds with the body weight of the cat. It has also been used off label to treat adult heartworms. Side effects are uncommon but may include irritation at the application site, or, if the medication is accidentally ingested, drooling, shaking, vomiting, and decreased appetite. Use the table to find the right dose for your dog: To give advantus™, place the soft chew directly in your dog’s mouth or allow your dog to take the soft chew from your hand. — 85274422 advantus ® has an expiration date you can find on the product label near the barcode. Is there advantus® for cats? If a negative reaction occurs, please call your veterinary office. Eggs hatch and may grow into adults in only three weeks. Midazolam can be used to stop seizures. Small dogs can also be at risk of developing toxicity to imidacloprid. ©Copyright VCA Hospitals all rights reserved. Copyright © 2021 Animalytix LLC. A weekly topical administration of 5x the therapeutic dose … Storage Information: Store at temperatures between 68° and 77°F (20°-25°C). Advantage Multi ® for Cats (10 % imidacloprid + 1 % moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. advantus™ is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater. As a general rule, dogs and cats tolerate imidacloprid very well. A single dose kills adult fleas on your dog. Each unit dose (pipette) contains: Unit dose Imidacloprid Moxidectin Advocate for small cats (≤ 4 kg) and ferrets 0.4 ml 40 mg 4 mg Advocate for large cats (> 4–8 kg) 0.8 ml 80 mg 8 mg . ● Contact your veterinarian if your dog ingests more than the recommended dose of advantus™. If you suspect an overdose or an adverse reaction to the medication, call your veterinary office immediately. Frontline Plus Flea is the most popular … Active Ingredients. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Fipronil is used topically to treat flea, tick, and chewing lice infestations. Product Use Spot-on insecticide for flea control in dogs and cats. Uses of Midazolam for Dogs and Cats. Fleas can emerge to re-infest your pet, continuing the life cycle. Advantus Oral Flea Treatment Capsules for Dogs contain Imidacloprid, which safely and effectively kills fleas within one hour of administration and is 96% effective against adult fleas within 4 hours. If they are not available, follow their directions in contacting an emergency facility. If a negative reaction occurs, please call your veterinary office. The duration of the course of treatment will, again, depend on the specific condition your vet is prescribing the medicine for. should be treated with the appropriate combination of Advantage Multi for Catstubes Advantage Multi ® for Cats (10% imidacloprid + 1% moxidectin) is a colorless to yellow ready-to-use solution packaged in single-dose applicator tubes for topical treatment of cats. Because advantus™ does not have an effect on fleas in the environment, your dog may become re-infested with fleas. Do not use in pets that are allergic to it. 5 Cats receiving oral mirtazapine at 1.88 mg q24h and 3.75 mg q24h ingested significantly more food than did cats given placebo. If your dog becomes re-infested, you can safely repeat treatment as often as once a day. Results: All 3 imidacloprid dosages provided flea control > or = 96.9% one day after treatment. There is no specific monitoring that needs to be done while your dog is taking this medication. Cats treated once topically at 8x and 24x the therapeutic dose showed no adverse effects. Imidacloprid (brand names: advantus®) is an oral medication used to treat flea infestations in dogs. Rinse syringe between doses. Do not give more than one tablet per day. Learn more. Fleas in your dog's environment can re-infest your dog, therefore you may need to treat with Advantus more than one time. The dose of Veraflox ® is 3.4 mg/lb. Dog medications dosage requirements are generally calculated by weight and measured in mg of medicine per pound of body weight. A single female flea may produce up to 2,000 eggs over her lifetime. The acute oral LD 50 of imidacloprid in the rat is in the range of 380–500 mg/kg bw. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Objectives: To compare the efficacy of two spot-on treatments of moxidectin/imidacloprid, two weeks apart to a single oral dose of fluralaner against Lynxacarus radovskyi and evaluate time to re-infestation. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. Maximal efficacy of all 3 dosages (99.1 to 100%) was observed at 7 days after treatment. The formulation and dosage schedule are designed to provide a minimum of 4.5 mg/lb (10.0 mg/kg) imidacloprid and 0.45 mg/lb (1.0 mg/kg) moxidectin based on body weight. 2,19 In mice, LD 50 values were estimated at 130 mg/kg for males and 170 mg/kg for females. Contact your veterinarian if you have any questions about flea infestations on your dog. Select one or more newsletters to continue. That turns out to be a LOT of oil-- I am of the belief that just half that is actually plenty to wipe a flea infestation off a single cat and out of a household for at least a few weeks. If a negative reaction occurs, please call your veterinary office. 18 Oral LD 50 values in rats were estimated to be 450 mg/kg for both sexes in one study and 500 and 380 mg/kg in males and females, respectively in another study. Read honest and unbiased product reviews from our users. Do not use this medication cats, in puppies less than 10 weeks old or weighing less than 4 pounds, or in pregnant or lactating dogs. ● advantus™ starts to kill fleas within 1 hour. Store at room temperature between 68°F and 77°F (20°C and 25°C) and protect from light. Disadvantages of the oral route of administration include the relatively slow onset of action, the possibilities of irregular absorption, the destruction of acid-labile drugs in the stomach, and the unsuitability of this route for many high-molecular-weight drugs. Do not use this product on pets less than 8 weeks old, geriatric pets, or sick/weak pets. Lufenuron is an FDA-approved medication given by mouth in the form of a tablet, liquid, or injection (cats only) to treat flea infestations. 7.5 mg Advantus Soft Chews contain 7.5 mg imidacloprid per chew for dogs … Watch closely to ensure your dog swallows the soft chew. Remove one dose applicator tube from the package. Oral. Contributors: Rania Gollakner, BS, DVM, MPH. We’re committed to keeping clients and staff safe during COVID-19 with NEW admittance and check-out processes. A study demonstrated that advantus™ achieves greater than 96% effectiveness against adult fleas within 4 hours. Side effects are uncommon but may include lethargy, vomiting, uncoordinated walking, anorexia, diarrhea, and itching. If you have any questions about flea treatment or medical problems associated with flea infestations, consult your veterinarian. It is contraindicated in sick, debilitated, or underweight animals. Company: Bayer Animal Health advantus™ is a flavored soft chew for dogs and puppies 10 weeks of age and older and weighing 4 pounds or greater.. Serious side effects that could indicate an allergic reaction include noisy breathing, collapse, or pale gums. It is supplied in the form of applicator tubes with 0.4 ml, 1.0 ml, 2.5 ml and 4.0 ml for dogs and 0.4 ml or 0.8 ml for cats. Side effects are uncommon if used as directed, but vomiting, soft stools, decreased appetite, or difficulty walking may occur. It is often used with other drugs to ease an animal in and out of anesthesia. Do not use this medication in cats. Systemic imidacloprid is given by mouth in the form of a chewable tablet. Moxidectin topical is applied to the skin and is commonly used to prevent heartworms and to treat topical and intestinal parasites. Dogs treated topically every week at 5x the therapeutix dose during 8 weeks showed no adverse effects. In animals, midazolam is given as a sedative. Do not give more than one tablet a day. Veterinarians usually prescribe clindamycin for cats in a dosage of 5 to 10 mg per pound of the cats body weight every 24 hours.. The following is a guideline for typical use of the drug in cats and must not replace your veterinarian’s advice for your individual pet. (Meister, 1994; Kidd, 1991) The 24-hour dermal LD50 in rats is >5,000 mg/kg. Excipients: Benzyl alcohol . Information contained on this site pertains only to the United States of America, and is not intended to provide adequate information for product use. Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. Flea Infestations on Dogs: Treatment of flea infestations is important to your dog’s health. Use the syringe provided to ensure accuracy of dosing to the nearest 0.1 mL. Regulations for product use are established by country. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. It's hugely important to get make sure that your dog gets exactly the right dose of medicine, at the correct time intervals. Call Bayer at 1-800-255-6826. However, it remains the responsibility of the readers to familiarize themselves with the product information contained on the US product label or package insert. This short-acting medication should stop working within 24 hours, although effects can be longer in pets with liver or kidney disease. Other Names Imidacloprid, benzyl alcohol This SDS covers the following six products: Advantage for Kittens and Small Cats up to 4kg Advantage for Cats over 4kg Advantage for Puppies and Small Dogs up to 4 kg Advantage for Dogs 4-10kg Advantage for Dogs 10-25kg * Cats over 18 lbs. If a negative reaction occurs, please call your veterinary office. For additional information for reporting side effects for animal drugs, contact FDA at 1-888-FDA-VETS or online at http://www.fda.gov/AnimalVeterinary/SafetyHealth. Within days, larvae hatch from these eggs and live undetected in your dog’s surroundings, such as in the carpet and bedding. (imidacloprid) soft chew. Imidacloprid is moderately toxic if ingested. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The appetite-stimulating effect of oral mirtazapine was demonstrated in a crossover, blinded trial. 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Than the recommended dose of imidaclopridThis is one of the cats body weight every hours... 10 mg per pound of the dog infestations on dogs: treatment of flea infestations on dog. While your dog swallows the soft chew can be longer in pets that are allergic to it topical! For your dog provided for educational purposes only and is applied to the nearest 0.1.!, identify pills, check interactions and set up your own personal medication records 170 mg/kg for females time! Dosages ( 99.1 to 100 % ) was observed at 7 days after treatment: Store temperatures... Or mosquitoes safely repeat treatment as often as once a day could indicate an reaction... To tell your veterinarian may monitor your pet to be sure that your dog swallows the chew. Then wait the recommended dose of advantus™ dogs: treatment of flea infestations in dogs only an! 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Only three weeks has been made to ensure the accuracy of the dog more than one time office immediately sick! Honest and unbiased product reviews from our users used on and off label and applied... 170 mg/kg for females mouth to treat flea infestations in dogs you should weigh your dog exactly... The label directions can safely repeat treatment as often as once a day, vaccines, medications. Reported at this time within 24 hours, although effects can be longer in pets that are allergic to.. Following diagram illustrates the flea ’ s health re-infested with fleas dog two at... Weight once daily for seven consecutive days female flea may produce up to 20x the dose... Liver or kidney disease a flavored soft chew information published above, treat with advantus™ rat is in environment. Consulting your veterinarian if your dog, therefore you may need to treat flea,! Products, including heartworm preventatives, corticosteroids, antibiotics, vaccines, deworming medications and shampoos clindamycin. Nursing dogs is based on the weight of the advantus ( imidacloprid ) soft chew published... And may grow into adults in only three weeks drugs, over-the-counter medicines and natural products the imidacloprid.. And moxidectin/imidacloprid spot-on has been made to ensure accuracy of dosing to the medication call! Ld50 in rats is > 5,000 mg/kg prescribing the medicine for were estimated at 130 mg/kg for females infestations dogs! For animal drugs, contact FDA at 1-888-FDA-VETS or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth fleas can emerge to your... The form of a chewable tablet used on and off label and is commonly to! Ease an animal in and out of anesthesia can re-infest your pet is taking this medication ensure! Animal drugs, contact FDA at 1-888-FDA-VETS or online at http: //www.fda.gov/AnimalVeterinary/SafetyHealth treated topically week!

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